YOUR TRUSTED PARTNER FOR API SUPPLY
& CDMO SERVICES
Protheragen delivers high-quality APIs and comprehensive CDMO services through a robust global supply chain. Our products span key therapeutic areas including cardiovascular, anti-infective, CNS, and oncology. With advanced, automated, and intelligent production lines, we ensure reliable quality and efficiency.Supported by strong R&D and scalable manufacturing, we provide one-stop CDMO solutions from early development to commercial production, partnering with leading biopharma companies worldwide.
Full-Scale Production Coverage
From gram-scale early-stage R&D to ton-scale commercial production, covering APIs, intermediates, and HPAPIs.
Global Presence
Strategic sites across China, the US, and Europe ensure agile response, IP protection, and secure data management.
Compliance & Quality
Certified by FDA, PMDA, and other global regulatory bodies. Robust ESG framework including wastewater treatment (50,000 tons/day) and a 20% carbon intensity reduction goal by 2030.
Diverse Technology Platforms
Cutting-edge capabilities in flow chemistry, synthetic biology, peptide synthesis, and PROTAC to accelerate drug development.
OUR CERTIFICATION
OUR CAPABILITIES
Protheragen is a U.S.-based supplier of high-quality APIs and custom CDMO services. We support projects of all sizes – from R&D quantities to commercial production – with a strong focus on quality, flexibility, and speed.
Global cGMP Sites
8 production bases across China, the US, Germany, and Japan. 4 FDA-inspected, 3 PMDA-certified, and 2 approved by EDQM.
Chemical Synthesis
11,000 m³ total capacity, 1,800+ reactors (50L–45,000L), with annual output of 4,000 tons of APIs and 38,000 tons of intermediates.
Biological Production
6,570 m³ total capacity, 172 reactors, with annual output of 2,000 tons of APIs and 2,000 tons of intermediates.
HPAPI Facilities
Dedicated workshops with isolator systems, reactor volumes ranging from 50L to 10,000L, handling OEB4/OEB5 projects.
US-based Warehouse
Strategically located in the U.S. Fast shipping, reduced lead times.
PLATFORMS
Peptide Platform
SPPS/LPPS synthesis with DAC-600 purification system; batch sizes up to 10 kg (short peptides up to tons).
Synthetic Biology
Over 3,000 tons of fermentation capacity annually, with 20+ enzymatic processes in commercial use.
ADC & PROTAC
GMP production of ADC toxins at 10 kg scale; 264+ PROTAC intermediates in stock.
Flow Chemistry
Experience with 30+ reaction types, from gram to kilogram scale for commercial applications.