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Ripretinib

Ripretinib

API0232966

Ripretinib

Riociguat is used to treat pulmonary arterial hypertension.

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API Description
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Related Patent Status

  • CAS No.

    1442472-39-0

  • Synonyms

    Ripretinib; 1442472-39-0; qinlock

  • CHEMBL ID

    CHEMBL4216467

  • Molecule Type

    Small molecule

  • Compound CID

    71584930

  • Molecular Weight (g/mol)

    510.4

  • Molecular Formula

    C24H21BrFN5O2

  • InChI

    InChI=1S/C24H21BrFN5O2/c1-3-31-21-12-22(27-2)28-13-14(21)9-17(23(31)32)16-10-20(19(26)11-18(16)25)30-24(33)29-15-7-5-4-6-8-15/h4-13H,3H2,1-2H3,(H,27,28)(H2,29,30,33)

  • InChIKey

    CEFJVGZHQAGLHS-UHFFFAOYSA-N

  • SMILES

    CCN1C2=CC(=NC=C2C=C(C1=O)C3=CC(=C(C=C3Br)F)NC(=O)NC4=CC=CC=C4)NC

  • IUPAC Name

    1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea

  • Exact Mass (Da)

    509.08627

  • Monoisotopic Mass (Da)

    509.08627

  • Patent No

    US11426390

  • First Approval

    2020

  • Patent Expire Date

    51360

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